Rachel Clipp

Rachel Clipp

Staff R&D Engineer

Dr. Rachel Clipp is a Staff Research and Development Engineer at Kitware. She joined Kitware in 2017 to conduct research in computational modeling and apply these solutions to biomedical problems. Since joining Kitware, she has worked to launch Pulse Physiology Engine, a fork of the TATRC-funded computational physiology engine. It has been incorporated in commercial and government-funded products and programs.

At Kitware, Dr. Clipp also works on high-fidelity computational fluid dynamic, including the Lattice-Boltzmann Method (LBM) and OpenFoam. As an example, she has worked with collaborators to analyze the upper airway for virtual surgery from medical imaging data through analysis with the LBM.

Throughout her career, Dr. Clipp has worked on a wide range of modeling and simulation problems. These projects include modeling the microvasculature of the liver to predict microsphere delivery to tumors and modeling the cerebral microvasculature to represent the effects of traumatic brain injury. She also served as the Lead Physiology Modeler on the TATRC-funded BioGears project, where she led the development of physiology models to represent different organ systems and feedback mechanisms in the human body.

Dr. Clipp’s graduate work focused on the development of dynamic boundary conditions for use in finite element analysis and computational fluid dynamics. The boundary conditions developed were used to predict the effects of respiration on the pulmonary vasculature. She also developed a benchtop apparatus to perfuse and ventilate excised lamb lungs to collect hemodynamic and respiratory data for validation of the dynamic boundary conditions.

Dr. Clip earned an M.S. and a Ph.D. in Biomedical Engineering from the joint program at the University of North Carolina at Chapel Hill and North Carolina State University. She completed her B.S. in Mechanical Engineering from Clemson University.

  1. F. Gessa, P. Asare, A. Bray, R. Clipp, and M. Poler, "Towards A Test and Validation Framework for Closed-Loop Physiology Management Systems for Critical and Perioperative Care," in Medical Cyber Physical Systems Workshop, 2018.
  2. R. Clipp, A. Bray, R. Metoyer, M. Thames, and J. Webb, "Pharmacokinetic and pharmacodynamic modeling in BioGears," in Proceedings of the International Conference of the IEEE Engineering in Medicine and Biology Society, 2016. [URL]
  3. M. Thames, J. Webb, R. Clipp, J. Carter, Z. Swarm, R. Metoyer, A. Bray, and D. Byrd, "Dynamic response to heat gain and heat loss in the biogears engine," in Proceedings of the Medicine Meets Virtual Reality Conference, 2016.
  4. Z. Swarm, J. Webb, R. Clipp, J. Carter, M. Thames, and R. Metoyer, "Modeling renal behavior and control in biogears," in Proceedings of the Medicine Meets Virtual Reality Conference, 2016.
  5. R. Metoyer, B. Bergeron, R. Clipp, J. Webb, M. Thames, Z. Swarm, J. Carter, Y. Gebremichael, and J. Heneghan, "Multiscale Simulation of Insults and Interventions: The BioGears Showcase Scenarios," in Proceedings of the Medicine Meets Virtual Reality Conference, 2016.
  6. R. Clipp, A. Bray, R. Metoyer, M. Thames, and J. Webb, "Pharmacokinetic and pharmacodynamic modeling in biogears," in Proceedings of the Medicine Meets Virtual Reality Conference, 2016.
  7. R. Clipp, M. Thames, J. Webb, R. Metoyer, Z. Swarm, and J. Carter, "Integration of a baroreflex model into a whole body physiology engine," in Summer Biomechanics, Bioengineering, and Biotransport Conference, 2016.
  8. R. Metoyer, J. Carter, B. Bergeron, A. Baird, A. Bray, R. Clipp, M. Thames, and J. Webb, "A framework for multiscale physiology: towards individualized computer simulation," in Virtual Physiological Human Conference, 2016.
  9. Y. Gebremichael, R. Clipp, J. Webb, A. Bray, M. Thames, Z. Swarm, J. Carter, and J. Heneghan, "Integration of a spontaneous respiratory driver with blood gas feedback into biogears, an open-source, whole-body physiology model," in Summer Biomechanics, Bioengineering, and Biotransport Conference, 2015.
  10. A. Kennedy, R. Clipp, and D. Christensen, "First-in-human fractal methodology for modeling the hepatic arterial tree and tumor microvasculature for 90 Y-microsphere brachytherapy.," Journal of Clinical Oncology, vol. 32, no. 3_suppl, pp. 248-248, Jan. 2014. [URL]
  11. S. Snarski, J. Webb, C. Volpe, A. Menozzi, T. Sherrill, D. Hope, H. Towles, B. Young, C. Stutts, R. Steffes, J. Rittenhour, B. Fisk, R. Clipp, M. Bennett, B. Church, M. TerMaath, B. Kaminski, M. Forgione, J. Beighley, B. Judge, J. Mauger, A. Adams, and M. Larson, "Passive infrared projectile tracking and geolocation of low quadrant elevation (low qe) rockets and mortars: system development and test results," in Military Sensing Symposia Passive Sensors Conference, 2014.
  12. G. Scott and R. Clipp, "Humansim: A physiology engine for the simulation of anesthesia/anaphylaxis training," in Military Health System Research Symposium, 2012.
  13. R. Clipp and B. Steele, "An evaluation of dynamic outlet boundary conditions in a 1D fluid dynamics model," Mathematical Biosciences and Engineering, vol. 9, no. 1, pp. 61-74, Dec. 2011. [URL]
  14. R. Clipp, "Computational Models of the Pulmonary Vasculature Including the Dynamic Effects of Respiration," Ph.D. dissertation, University of North Carolina at Chapel Hill / North Carolina State University, 2010.
  15. R. Clipp and B. Steele, "Impedance Boundary Conditions for the Pulmonary Vasculature Including the Effects of Geometry, Compliance, and Respiration," IEEE Transactions on Biomedical Engineering, vol. 56, no. 3, pp. 862-870, Mar. 2009. [URL]
  16. R. Clipp and B. Steele, "Comparison of three types of dynamic boundary conditions," in Proceedings of the ASME Summer Bioengineering Conference, 2009. [URL]
  17. R. Clipp and B. Steele, "A Dynamic Boundary Condition for the Pulmonary Vasculature," in Proceedings of the ASME Summer Bioengineering Conference, 2008. [URL]
  18. R. Clipp and B. Steele, "Boundary conditons for the pulmonary vasculature," in Institue of Biological Engineering Annual Conference, 2008.
  19. R. Clipp and B. Steele, "Toward Determining a Dynamic Impedance Boundary Condition," in Proceedings of the ASME Summer Bioengineering Conference, 2007. [URL]
  20. R. Clipp, "Determination of Impedance Boundary Conditions for the Pulmonary Vasculature," M.S. thesis, University of North Carolina at Chapel Hill / North Carolina State University, 2007.
  21. R. Clipp and B. Steele, "Dynamic cardio-pulmonary impedance boundary conditions," in Biomedical Engineering Society Fall Conference, 2007.