Stephen Aylward

Stephen Aylward

Senior Director of Strategic Initiatives

Dr. Aylward is Senior Director of Strategic Initiatives and founder of Kitware’s office in North Carolina. He also help directs Kitware’s medical research activities. At the University of North Carolina (UNC), Dr. Aylward is an adjunct associate professor in the Department of Computer Science. He volunteers as the treasurer for the Insight Software Consortium that helps to manage ITK, IGSTK, and other open-source packages for medical image analysis. He also serves as an associate editor for IEEE Transactions on Medical Imaging and the SPIE Journal of Medical Imaging, a board member for the MICCAI society and on several conference and academic advisory committees. Prior to joining Kitware, Dr. Aylward was a tenured associate professor of Radiology, Computer Science, and Surgery at UNC.

In general, Dr. Aylward’s research has focused on vascular image analysis, computer-aided diagnosis, intra-operative registration of ultrasound with pre-operative images, and developing ITK and other open-source toolkits. At Kitware the majority of his work focuses on research involving point-of-care ultrasound and vascular image analysis. He has had NIH, NSF, and DoD R01, SBIR, and STTR grants to (a) work with a small businesses to develop a low-cost, easy to use ultrasound systems that help novice uses assess intra-abdominal bleeding for trauma victims in the field, (b) assist a university professor in the study the micro-vasculature of tumors using micro-bubble contrast agents to grade cancers and study their response to treatment, (c) assist a small business to create a commercial ultrasound system that forms whole body 3D ultrasound scans of mice to detect genetic variations and to characterize disease, (d) enhance the capabilities of VTK for medical imaging, and (e) collaborator with leading institutions on the study of traumatic brain injury. Dr. Aylward has been involved in these and related research areas for nearly 25 years.

  1. S. R. Aylward et al., "Ultrasound spectroscopy,"2016, pp. 1013-1016.
  2. T. Kapur et al., Increasing the impact of medical image computing using community-based open-access hackathons: The NA-MIC and 3D Slicer experience,2016.
  3. S. E. Shelton, P. A. Dayton, S. R. Aylward, and F. S. Foster, "The application of acoustic angiography to assess the progression of angiogenesis in a spontaneous mouse model of breast cancer,"2016, pp. 1-3.
  4. S. E. Shelton, B. D. Lindsey, R. Gessner, Y. Lee, S. Aylward, H. Lee, E. Cherin, F. S. Foster, and P. A. Dayton, "Acoustic angiography: a new high frequency contrast ultrasound technique for biomedical imaging,"2016, pp. 987109-987109.
  5. X. Yang, X. Han, E. Park, S. Aylward, R. Kwitt, and M. Niethammer, "Registration of Pathological Images,"2016, pp. 97-107.
  6. X. Liu, M. Niethammer, R. Kwitt, N. Singh, M. McCormick, and S. Aylward, "Low-rank atlas image analyses in the presence of pathologies," IEEE transactions on medical imaging, vol. 34, no. 12, pp. 2583-2591 2015.
  7. B. Paniagua, D. Zukic, R. Ortiz, S. Aylward, B. Golden, T. Nguyen, and A. Enquobahrie, "Ultrasound-Guided Navigation System for Orthognathic Surgery,"2015, pp. 1-10.
  8. S. E. Shelton, Y. Z. Lee, M. Lee, E. Cherin, F. S. Foster, S. R. Aylward, and P. A. Dayton, "Quantification of microvascular tortuosity during tumor evolution using acoustic angiography," Ultrasound in medicine \& biology, vol. 41, no. 7, pp. 1896-1904 2015.
  9. J. Finet, R. Ortiz, J. Andruejol, A. Enquobahrie, J. Jomier, J. Payne, and S. Aylward, "Bender: An Open Source Software for Efficient Model Posing and Morphing,"2014, pp. 203-210.
  10. R. Kwitt, S. Razzaque, J. Lowell, and S. Aylward, "Variability sensitivity of dynamic texture based recognition in clinical CT data,"2014, pp. 903420-903420.
  11. X. Liu, M. Niethammer, R. Kwitt, M. McCormick, and S. Aylward, "Low-rank to the rescue--atlas-based analyses in the presence of pathologies,"2014, pp. 97-104.
  12. S. Aylward, "Trends and challenges in open source software (Presentation Video),"2013, pp. 885501-885501.
  13. A. Enquobahrie, V. Shivaprabhu, S. Aylward, J. Finet, K. Cleary, and R. Alterovitz, "Patient-specific port placement for laparoscopic surgery using atlas-based registration,"2013, pp. 86711-86711.
  14. R. C. Gessner, A. D. Hanson, S. Feingold, A. T. Cashion, A. Corcimaru, B. T. Wu, C. R. Mullins, S. R. Aylward, L. M. Reid, and P. A. Dayton, "Functional ultrasound imaging for assessment of extracellular matrix scaffolds used for liver organoid formation," Biomaterials, vol. 34, no. 37, pp. 9341-9351 2013.
  15. R. Kwitt, D. Pace, M. Niethammer, and S. Aylward, "Studying cerebral vasculature using structure proximity and graph kernels,"2013, pp. 534-541.
  16. R. Kwitt, N. Vasconcelos, S. Razzaque, and S. Aylward, "Localizing target structures in ultrasound video--a phantom study," Medical image analysis, vol. 17, no. 7, pp. 712-722 2013.
  17. D. F. Pace, S. R. Aylward, and M. Niethammer, "A locally adaptive regularization based on anisotropic diffusion for deformable image registration of sliding organs," IEEE transactions on medical imaging, vol. 32, no. 11, pp. 2114-2126 2013.
  18. B. Paniagua, O. Emodi, J. Hill, J. Fishbaugh, L. A. Pimenta, S. R. Aylward, E. Andinet, G. Gerig, J. Gilmore, V. A. J. A, and others, "3D of brain shape and volume after cranial vault remodeling surgery for craniosynostosis correction in infants,"2013, pp. 86720-86720.
  19. V. R. Shivaprabhu, A. Enquobahrie, Z. Mullen, and S. Aylward, "Accelerating ultrasound image analysis research through publically available database,"2013, pp. 867517-867517.
  20. S. Aylward et al., Methods, systems, and computer program products for hierarchical registration between a blood vessel and tissue surface model for a subject and a blood vessel and tissue surface image for the subject,2012.
  21. A. Fedorov et al., "3D Slicer as an image computing platform for the Quantitative Imaging Network," Magnetic resonance imaging, vol. 30, no. 9, pp. 1323-1341 2012.
  22. R. C. Gessner, S. R. Aylward, and P. A. Dayton, "Mapping microvasculature with acoustic angiography yields quantifiable differences between healthy and tumor-bearing tissue volumes in a rodent model," Radiology, vol. 264, no. 3, pp. 733-740 2012.
  23. A. Irimia, B. Wang, S. R. Aylward, M. W. Prastawa, D. F. Pace, G. Gerig, D. A. Hovda, R. Kikinis, P. M. Vespa, and V. H. J. D, "Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction," NeuroImage: Clinical, vol. 1, no. 1, pp. 1-17 2012.
  24. T. Kapur, S. Pieper, R. Whitaker, S. Aylward, M. Jakab, W. Schroeder, and R. Kikinis, "The National Alliance for Medical Image Computing, a roadmap initiative to build a free and open source software infrastructure for translational research in medical image analysis," Journal of the American Medical Informatics Association, vol. 19, no. 2, pp. 176-180 2012.
  25. R. Kwitt, N. Vasconcelos, S. Razzaque, and S. Aylward, "Recognition in ultrasound videos: where am I?," Medical Image Computing and Computer-Assisted Intervention--MICCAI 2012, pp. 83-90 2012.
  26. D. Testi, D. Giunchi, G. Clapworthy, S. Aylward, X. Planes, and R. Christie, "New interactive visualisation of multiscale biomedical data,"2012, pp. 76.
  27. M. A. Audette, D. Rivi{\`e}re, C. Law, L. Ibanez, S. R. Aylward, J. Finet, X. Wu, and M. G. Ewend, "Approach-specific multi-grid anatomical modeling for neurosurgery simulation with public-domain and open-source software,"2011, pp. 79642-79642.
  28. M. Niethammer, G. L. Hart, D. F. Pace, P. M. Vespa, A. Irimia, V. H. J. D, and S. R. Aylward, "Geometric metamorphosis,"2011, pp. 639-646.
  29. D. F. Pace, A. Enquobahrie, H. Yang, S. R. Aylward, and M. Niethammer, "Deformable image registration of sliding organs using anisotropic diffusive regularization,"2011, pp. 407-413.
  30. D. F. Pace, M. Niethammer, and S. R. Aylward, "Sliding geometries in deformable image registration,"2011, pp. 141-148.
  31. E. Bullitt, D. Zeng, B. Mortamet, A. Ghosh, S. R. Aylward, W. Lin, B. L. Marks, and K. Smith, "The effects of healthy aging on intracerebral blood vessels visualized by magnetic resonance angiography," Neurobiology of aging, vol. 31, no. 2, pp. 290-300 2010.
  32. R. C. Gessner, R. Kothadia, S. Feingold, S. Aylward, E. Bullitt, and P. A. Dayton, "Blood vessel structural morphology derived from 3D dual-frequency ultrasound images,"2010, pp. 209-212.
  33. E. Bullitt, M. Ewend, J. Vredenburgh, A. Friedman, W. Lin, K. Wilber, D. Zeng, S. R. Aylward, and D. Reardon, "Computerized assessment of vessel morphological changes during treatment of glioblastoma multiforme: report of a case imaged serially by MRA over four years," Neuroimage, vol. 47, pp. 143-151 2009.
  34. J. Jomier, S. R. Aylward, C. Marion, J. Lee, and M. Styner, "A digital archiving system and distributed server-side processing of large datasets,"2009, pp. 726413-726413.
  35. J. Lee, J. Jomier, S. Aylward, M. Tyszka, S. Moy, J. Lauder, and M. Styner, "Evaluation of atlas based mouse brain segmentation,"2009, pp. 725943-725943.
  36. G. Piliere, V. H. M. H, R. Dixon, J. Stavas, S. Aylward, and E. Bullitt, "Vessel target location estimation during the TIPS procedure," Medical image analysis, vol. 13, no. 3, pp. 519-529 2009.
  37. I. Oguz, J. Cates, T. Fletcher, R. Whitaker, D. Cool, S. Aylward, and M. Styner, "Cortical correspondence using entropy-based particle systems and local features,"2008, pp. 1637-1640.
  38. Z. Zhao, D. Wallace, S. Freedman, and S. Aylward, "A tool for computer-aided diagnosis of retinopathy of prematurity [6915-104],"2008, pp. 6915.
  39. Z. Zhao, D. K. Wallace, S. F. Freedman, and S. R. Aylward, "A tool for computer-aided diagnosis of retinopathy of prematurity,"2008, pp. 69152-69152.
  40. E. Bullitt, S. R. Aylward, V. D. T, and W. Lin, "Computer-assisted measurement of vessel shape from 3T magnetic resonance angiography of mouse brain," Methods, vol. 43, no. 1, pp. 29-34 2007.
  41. P. Cheng, L. Ibanez, D. Gobbi, K. Gary, S. Aylward, J. Jomier, A. Enquobahrie, H. Zhang, H. Kim, and M. Blake, "The Image-Guided Surgery ToolKit IGSTK: an open source C++ software toolkit [6516-09],"2007, pp. 65160.
  42. P. Cheng, L. Ibanez, D. Gobbi, K. Gary, S. Aylward, J. Jomier, A. Enquobahrie, H. Zhang, H. Kim, M. B. Blake, and others, "The Image-Guided Surgery ToolKit IGSTK: an open source C++ software toolkit,"2007, pp. 65160-65160.
  43. S. DiMaio, T. Kapur, K. Cleary, S. Aylward, P. Kazanzides, K. Vosburgh, R. Ellis, J. Duncan, K. Farahani, H. Lemke, and others, "Challenges in image-guided therapy system design," NeuroImage, vol. 37, pp. 144-151 2007.
  44. A. Enquobahrie, P. Cheng, K. Gary, L. Ibanez, D. Gobbi, F. Lindseth, Z. Yaniv, S. Aylward, J. Jomier, and K. Cleary, "The image-guided surgery toolkit IGSTK: an open source C++ software toolkit," Journal of Digital Imaging, vol. 20, no. 1, pp. 21-33 2007.
  45. P. Cheng, H. Zhang, H. Kim, K. Gary, M. B. Blake, D. Gobbi, S. Aylward, J. Jomier, A. Enquobahrie, R. Avila, and others, "IGSTK: Framework and example application using an open source toolkit for image-guided surgery applications,"2006, pp. 61411-61411.
  46. K. Gary, L. Ibanez, S. Aylward, D. Gobbi, M. B. Blake, and K. Cleary, "IGSTK: an open source software toolkit for image-guided surgery," Computer, vol. 39, no. 4, pp. 46-53 2006.
  47. L. Ib{\'a}{\~n}ez, R. Avila, and S. Aylward, "Open source and open science: how it is changing the medical imaging community,"2006, pp. 690-693.
  48. J. Jomier, E. Bullitt, V. H. Mark, C. Pathak, and S. R. Aylward, "3D/2D model-to-image registration applied to TIPS surgery,"2006, pp. 662-669.
  49. S. Aylward et al., "Intraoperative image processing for surgical guidance," IEEE transactions on medical imaging, vol. 24, no. 11, pp. 1401-1404 2005.
  50. S. Aylward et al., "Spatial graphs for intra-cranial vascular network characterization, generation, and discrimination," Medical Image Computing and Computer-Assisted Intervention--MICCAI 2005, pp. 59-66 2005.
  51. E. Bullitt and S. Aylward, "Visualizing blood vessel trees in three dimensions: clinical applications,"2005, pp. 67-78.
  52. E. Bullitt, K. E. Muller, I. Jung, W. Lin, and S. Aylward, "Analyzing attributes of vessel populations," Medical image analysis, vol. 9, no. 1, pp. 39-49 2005.
  53. E. Bullitt, D. Zeng, G. Gerig, S. Aylward, S. Joshi, J. K. Smith, W. Lin, and M. G. Ewend, "Vessel tortuosity and brain tumor malignancy: a blinded study1," Academic radiology, vol. 12, no. 10, pp. 1232-1240 2005.
  54. E. B. Cole, E. D. Pisano, D. Zeng, K. Muller, S. R. Aylward, S. Park, C. Kuzmiak, M. Koomen, D. Pavic, R. Walsh, and others, "The Effects of Gray Scale Image Processing on Digital Mammography Interpretation Performance 1," Academic radiology, vol. 12, no. 5, pp. 585-595 2005.
  55. L. Ibanez, G. Kindlmann, and S. Aylward, "Hot topics in 3D medical image visualization,"2005, pp. 1.
  56. J. Jomier, V. LeDigarcher, and S. Aylward, "Comparison of vessel segmentations using staple," Medical Image Computing and Computer-Assisted Intervention--MICCAI 2005, pp. 523-530 2005.
  57. J. Jomier, V. LeDigarcher, and S. Aylward, "Automatic vascular tree formation using the mahalanobis distance," Medical Image Computing and Computer-Assisted Intervention--MICCAI 2005, pp. 806-812 2005.
  58. K. Kocis, C. Kuroda, W. Sternberger, J. Michael, L. Ramac-Thomas, S. Daniels, S. Aylward, J. Kim, D. Nichols, J. Gotsis, and others, "Quantifying Diaphragm Function with Ultrasound: Development in a Piglet Model of Diaphragm Fatigue: 19," Pediatric Critical Care Medicine, vol. 6, no. 1, pp. 107 2005.
  59. D. Shelton, G. Stetten, S. Aylward, L. Ib{\'a}{\~n}ez, A. Cois, and C. Stewart, "Teaching medical image analysis with the insight toolkit," Medical image analysis, vol. 9, no. 6, pp. 605-611 2005.
  60. Z. Zhao, S. R. Aylward, and E. K. Teoh, "A novel 3D partitioned active shape model for segmentation of brain MR images,"2005, pp. 221-228.
  61. S. R. Aylward et al., Systems and methods for tubular object processing,2004.
  62. S. R. Aylward and J. Kim, "Statistics of pattern recognition," in Insight into Images: Principles and Practice for Segmentation, Registration, and Image Analysis.2004, pp. 47-101
  63. .
  64. E. Bullitt, M. G. Ewend, S. Aylward, W. Lin, G. Gerig, S. Joshi, I. Jung, K. Muller, and J. K. Smith, "Abnormal vessel tortuosity as a marker of treatment response of malignant gliomas: preliminary report," Technology in cancer research \& treatment, vol. 3, no. 6, pp. 577-584 2004.
  65. E. Bullitt, I. Jung, K. Muller, G. Gerig, S. Aylward, S. Joshi, K. Smith, W. Lin, and M. Ewend, "Determining malignancy of brain tumors by analysis of vessel shape," Medical Image Computing and Computer-Assisted Intervention--MICCAI 2004, pp. 645-653 2004.
  66. Y. Fridman, S. M. Pizer, S. Aylward, and E. Bullitt, "Extracting branching tubular object geometry via cores," Medical image analysis, vol. 8, no. 3, pp. 169-176 2004.
  67. J. Jomier and S. Aylward, "Rigid and deformable vasculature-to-image registration: A hierarchical approach," Medical Image Computing and Computer-Assisted Intervention--MICCAI 2004, pp. 829-836 2004.
  68. J. Jomier, E. Rault, and S. R. Aylward, "Automatic quantification of pupil dilation under stress,"2004, pp. 249-252.
  69. J. Jomier, S. Weeks, and S. R. Aylward, "Vascular image registration for intra-operative 3D ultrasound annotation,"2004, pp. 1308.
  70. K. C. Kocis, M. Cereda, C. A. Kuroda, H. L. Hurd, S. R. Aylward, E. B. Freid, J. R. Yankaskas, and W. I. Sternberger, "AREADI, A NOVEL ULTRASOUND METHOD FOR QUANTIFYING DIAPHRAGM FUNCTION IN ADULTS: 394," Critical Care Medicine, vol. 32, no. 12, pp. 109 2004.
  71. K. A. Tucker, K. R. Robertson, W. Lin, J. K. Smith, H. An, Y. Chen, S. R. Aylward, and C. D. Hall, "Neuroimaging in human immunodeficiency virus infection," Journal of neuroimmunology, vol. 157, no. 1, pp. 153-162 2004.
  72. S. R. Aylward et al., "Registration and analysis of vascular images," International Journal of Computer Vision, vol. 55, no. 2-3, pp. 123-138 2003.
  73. S. Aylward and E. Bullitt, "Clinical Applications Involving Vascular Image Segmentation and Registration," in Angiography and Plaque Imaging: Advanced Segmentation Techniques.2003, pp. 451-499
  74. .
  75. E. Bullitt, G. Gerig, S. Aylward, S. Joshi, K. Smith, M. Ewend, and W. Lin, "Vascular attributes and malignant brain tumors,"2003, pp. 671-679.
  76. E. Bullitt, G. Gerig, S. M. Pizer, W. Lin, and S. R. Aylward, "Measuring tortuosity of the intracerebral vasculature from MRA images," IEEE transactions on medical imaging, vol. 22, no. 9, pp. 1163-1171 2003.
  77. D. Chillet, J. Jomier, D. Cool, and S. Aylward, "Vascular atlas formation using a vessel-to-image affine registration method," Medical Image Computing and Computer-Assisted Intervention-MICCAI 2003, pp. 335-342 2003.
  78. D. Cool, D. Chillet, J. Kim, J. Guyon, M. Foskey, and S. Aylward, "Tissue-Based Affine Registration of Brain Images to form a Vascular Density Atlas," Lecture Notes in Computer Science, vol. 2879, pp. 9-15 2003.
  79. D. Cool, D. Chillet, J. Kim, J. Guyon, M. Foskey, and S. Aylward, "Tissue-based affine registration of brain images to form a vascular density atlas,"2003, pp. 9-15.
  80. Y. Fridman, S. Pizer, S. Aylward, and E. Bullitt, "Segmenting 3D branching tubular structures using cores," Medical Image Computing and Computer-Assisted Intervention-MICCAI 2003, pp. 570-577 2003.
  81. J. Guyon, M. Foskey, J. Kim, Z. Firat, B. Davis, K. Haneke, and S. R. Aylward, "VETOT, volume estimation and tracking over time: Framework and validation,"2003, pp. 142-149.
  82. B. Jolly, V. H. Mark, S. Aylward, and E. Bullitt, "Needle detection and tracking in the TIPS endovascular procedure,"2003, pp. 953-954.
  83. J. Jomier, D. K. Wallace, and S. R. Aylward, "Quantification of retinopathy of prematurity via vessel segmentation,"2003, pp. 620-626.
  84. S. Laxminarayan and J. S. Suri, Angiography and plaque imaging: advanced segmentation techniques,2003.
  85. S. M. Pizer, G. Gerig, S. Joshi, and S. R. Aylward, "Multiscale medial shape-based analysis of image objects," Proceedings of the IEEE, vol. 91, no. 10, pp. 1670-1679 2003.
  86. D. Wallace, C. J. A, J. Jomier, S. Aylward, L. I. MB, M. Trese, P. S. Group, and others, "Computer Automated Quantification of Plus Disease in RetCam Images of Retinopathy of Prematurity," Investigative Ophthalmology \& Visual Science, vol. 44, no. 13, pp. 588-588 2003.
  87. D. K. Wallace, J. Jomier, S. R. Aylward, and M. B. Landers, "Computer-automated quantification of plus disease in retinopathy of prematurity," Journal of American Association for Pediatric Ophthalmology and Strabismus, vol. 7, no. 2, pp. 126-130 2003.
  88. S. R. Aylward, "Continuous mixture modeling via goodness-of-fit ridges," Pattern recognition, vol. 35, no. 9, pp. 1821-1833 2002.
  89. S. R. Aylward and E. Bullitt, "Initialization, noise, singularities, and scale in height ridge traversal for tubular object centerline extraction," IEEE transactions on medical imaging, vol. 21, no. 2, pp. 61-75 2002.
  90. S. R. Aylward et al., "Intra-operative 3D ultrasound augmentation,"2002, pp. 421-424.
  91. E. Bullitt and S. Aylward, "Patient-specific vascular models for endovascular and open operative procedures,"2002, pp. 129-138.
  92. E. Bullitt and S. R. Aylward, "Volume rendering of segmented image objects," IEEE Transactions on Medical Imaging, vol. 21, no. 8, pp. 998-1002 2002.
  93. L. Ibanez, L. Ng, J. Gee, and S. Aylward, "Registration patterns: the generic framework for image registration of the Insight Toolkit,"2002, pp. 345-348.
  94. T. S. Yoo, M. J. Ackerman, W. E. Lorensen, W. Schroeder, V. Chalana, S. Aylward, D. Metaxas, and R. Whitaker, "Engineering and algorithm design for an image processing API: a technical report on ITK-the insight toolkit," Studies in health technology and informatics, pp. 586-592 2002.
  95. S. Aylward et al., "Analysis of the parameter space of a metric for registering 3D vascular images,"2001, pp. 932-939.
  96. E. Bullitt and S. Aylward, "Volume rendering of segmented tubular objects,"2001, pp. 161-168.
  97. E. Bullitt and S. R. Aylward, "Analysis of time-varying images using 3D vascular models,"2001, pp. 9-14.
  98. E. Bullitt, S. Aylward, B. J. E. J, and G. Gerig, "Computer-assisted visualization of arteriovenous malformations on the home personal computer," Neurosurgery, vol. 48, no. 3, pp. 576-583 2001.
  99. E. Bullitt, S. Aylward, K. Smith, S. Mukherji, M. Jiroutek, and K. Muller, "Symbolic description of intracerebral vessels segmented from magnetic resonance angiograms and evaluation by comparison with X-ray angiograms," Medical Image Analysis, vol. 5, no. 2, pp. 157-169 2001.
  100. M. Rosenthal, S. Weeks, S. Aylward, E. Bullitt, and H. Fuchs, "Intraoperative tracking of anatomical structures using fluoroscopy and a vascular balloon catheter,"2001, pp. 1253-1254.
  101. S. Weeks, K. Wilber, and S. Aylward, "Volume estimations using conventional hand tracing techniques vs automatic thresholding techniques: Can we be more accurate and save time?,"2001, pp. 119-119.
  102. R. J. Gerstle, S. R. Aylward, S. Kromhout-Schiro, and S. K. Mukherji, "The role of neural networks in improving the accuracy of MR spectroscopy for the diagnosis of head and neck squamous cell carcinoma," American journal of neuroradiology, vol. 21, no. 6, pp. 1133-1138 2000.
  103. E. D. Pisano, E. B. Cole, B. M. Hemminger, M. J. Yaffe, S. R. Aylward, A. D. Maidment, R. E. Johnston, M. B. Williams, L. T. Niklason, E. F. Conant, and others, "Image Processing Algorithms for Digital Mammography: A Pictorial Essay 1," Radiographics, vol. 20, no. 5, pp. 1479-1491 2000.
  104. E. D. Pisano et al., "Radiologists Preferences for Digital Mammographic Display 1," Radiology, vol. 216, no. 3, pp. 820-830 2000.
  105. E. Bullitt, S. Aylward, A. Liu, J. Stone, S. K. Mukherji, C. Coffey, G. Gerig, and S. M. Pizer, "3d graph description of the intracerebral vasculature from segmented mra and tests of accuracy by comparison with x-ray angiograms,"1999, pp. 308-321.
  106. E. Bullitt, A. Liu, S. R. Aylward, C. Coffey, J. Stone, S. K. Mukherji, K. E. Muller, and S. M. Pizer, "Registration of 3D cerebral vessels with 2D digital angiograms: Clinical evaluation," Academic Radiology, vol. 6, no. 9, pp. 539-546 1999.
  107. B. Hemminger, E. Cole, S. Zong, M. Yaffe, S. Aylward, A. Maidment, M. Williams, L. Niklason, R. Johnston, and E. Pisano, "Evaluation of digital processing methods for the display of digital mammography [3658-44],"1999, pp. 382-395.
  108. B. M. Hemminger, E. Cole, S. Zong, M. J. Yaffe, S. Aylward, A. D. Maidment, M. B. Williams, L. T. Niklason, R. E. Johnston, and E. D. Pisano, "Evaluation of digital processing methods for the display of digital mammography,"1999, pp. 382-393.
  109. E. Pisano, B. Hemminger, S. Sthapit, S. Aylward, E. Cole, and R. Johnston, "Comparison of speed and accuracy of a digital mammography softcopy display system vs. printed film display,"1999, pp. 322-322.
  110. S. Aylward et al., "VTree3D: Fast and effective vessel, bronchial tube, duct, and bone display,"1998, pp. 394-394.
  111. S. R. Aylward et al., "Mixture modeling for digital mammogram display and analysis," in Digital Mammography.1998, pp. 305-312
  112. .
  113. R. Gerstle, S. Aylward, S. Mukherji, S. Schiro, and K. Muller, "Neural network and statistical analysis of proton MR spectroscopy in the diagnosis of laryngeal carcinoma,"1998, pp. 151-151.
  114. S. R. Aylward, "Continuous mixture modeling via goodness-of-fit cores," Medical Physics, vol. 24, no. 7, pp. 1182-1182 1997.
  115. S. Aylward and S. Pizer, "Continuous gaussian mixture modeling,"1997, pp. 176-189.
  116. E. Bullitt, A. Liu, S. Aylward, and S. Pizer, "Reconstruction of the intracerebral vasculature from MRA and a pair of projection views,"1997, pp. 537-542.
  117. E. Bullitt, A. Liu, S. Aylward, M. Soltys, J. Rosenman, and S. M. Pizer, "Methods for displaying intracerebral vascular anatomy.," American journal of neuroradiology, vol. 18, no. 3, pp. 417-420 1997.
  118. S. Aylward et al., "Intensity ridge and widths for tubular object segmentation and description,"1996, pp. 131-138.
  119. G. E. Peterson, D. S. Clair, S. R. Aylward, and W. E. Bond, "Using Taguchi's method of experimental design to control errors in layered perceptrons," IEEE transactions on neural networks, vol. 6, no. 4, pp. 949-961 1995.
  120. S. Aylward et al., "Spatially invariant classification of tissues in MR images [2359-31],"1994, pp. 352-352.
  121. R. J. Anderson and S. R. Aylward, "Lab testing of neural networks for improved aircraft onboard-diagnostics on flight-ready hardware,"1993, pp. 404-410.
  122. D. C. S. Clair, G. E. Peterson, S. Aylward, and W. E. Bond, "Design techniques for the control of errors in backpropagation neural networks,"1993, pp. 372-383.
  123. S. C. DC, G. Peterson, S. Aylward, and W. Bond, "Design techniques for the control of errors in backpropagation neural networks [1966-26],"1993, pp. 372-372.
  124. W. E. Bond, S. C. DC, M. Amirfathi, C. J. Merz, and S. Aylward, "Neural network analysis of nondestructive evaluation patterns,"1992, pp. 643-650.
  125. S. C. D. C, W. E. Bond, A. Rigler, and S. Aylward, "An evaluation of learning performance in backpropagation neural networks and decision-tree classifier systems,"1992, pp. 636-642.
  126. D. C. S. Clair, W. Bond, A. Rigler, and S. Aylward, "Evaluation of Neural Network and Decision-Tree Classifier System Performance Using Learning Accuracy Techniques,"1991, pp. 161.
  127. A. Rigler and S. Aylward, "Evaluation of Neural Network and Decision-Tree Classifier System Performance Using Learning Accuracy Techniques Daniel C. St. Clair* University of Missouri-Rolla,"1991, pp. 161.
  128. , "Registering Fiber Tracts with Fractional Anisotropy for Functional Sites Localization," .
  129. , "Improved Inter-Subject Spatial Localization of Neuro-Functional Activation through Cerebrovascular Alignment," .
  130. S. AYLWARD and R. ANDERSON, "An algorithm for neural network architecture generation,"pp. 3756.
  131. S. Aylward et al., "Spatially invariant classification of tissues in MR images," .
  132. S. Aylward et al., "The effects of magnetic resonance image inhomogeneities on automated tissue classification," TR94-021, University of North Carolina, Chapel Hill .
  133. S. Aylward and L. M. Hadjiiski, "Medical Imaging 2014: Computer-Aided Diagnosis," .
  134. S. Aylward et al., "Optimizing ITK’s registration methods for multi-processor, shared-memory systems," Insight Journal .
  135. M. B. Blake, K. Cleary, H. Kim, S. Ranjan, K. Gary, J. Jomier, S. Aylward, and L. Ibanez, "Component-based design and development for robust medical applications," .
  136. H. Buchanan et al., "DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH NATIONAL LIBRARY OF MEDICINE MINUTES OF THE BOARD OF REGENTS September 9-10, 2003," .
  137. E. Bullitt, A. Liu, S. Aylward, and S. M. Pizer, "3D reconstruction of aneurysms from projection angiograms," British Journal of Neurosurgery, vol. 11, no. 5, pp. 458-459 .
  138. E. Bullitt, I. Jung, K. Muller, G. Gerig, S. Aylward, S. Joshi, K. Smith, W. Lin, and M. Ewend, "Lecture Notes in Computer Science," .
  139. D. Dalal, J. Jomier, and S. Aylward, "A DICOM-based Software Infrastructure for Data Archiving," .
  140. A. Enquobahrie, V. Shivaprabhu, S. Aylward, J. Finet, K. Cleary, and R. Alterovitz, "Medical Imaging 2013: Image-Guided Procedures, Robotic Interventions, and Modeling," .
  141. K. Gary, B. Blake, S. Aylward, J. Jomier, D. Gobbi, H. S. Kim, R. Avila, L. Ibanez, and K. Cleary, "IGSTK: Development Process and Project Management Best Practices for an Open Source Software Toolkit for Image-Guided Surgery Applications," .
  142. R. C. Gessner, S. R. Aylward, and P. A. Dayton, "Imaging tortuosity: the potential utility of acoustic angiography in cancer detection and tumor assessment," Imaging, vol. 4, no. 6, pp. 581-583 .
  143. X. Han, X. Yang, S. Aylward, R. Kwitt, and M. Niethammer, "Efficient Registration of Pathological Images: A Joint PCA/Image-Reconstruction Approach," arXiv preprint arXiv:1704.00036 .
  144. L. Ibanez, J. Jomier, D. Gobbi, R. Avila, M. B. Blake, H. Kim, K. Gary, S. Aylward, and K. Cleary, "IGSTK: A State machine architecture for an open source software toolkit for image-guided surgery applications," .
  145. B. Jolly, V. H. M, S. Aylward, and E. Bullitt, "Needle tracking and detection in the TIPS endovascular procedure,"pp. 953-954.
  146. J. Jomier and S. R. Aylward, "Vessel to Image Registration using Rigid and Elastic Transformations," Procs MICCAI .
  147. C. Mullins, R. Gessner, and S. Aylward, "Using TubeTK to Automatically Merge Volumes," Insight Journal .
  148. C. L. Novak and S. Aylward, "Medical Imaging 2013: Computer-Aided Diagnosis," .
  149. C. L. Novak and S. Aylward, "Computer-Aided Diagnosis,"pp. 867001-1.
  150. D. F. Pace, M. Niethammer, and S. R. Aylward, "Abdominal Imaging: Computational and Clinical Applications-Third International Workshop, Held in Conjunction with MICCAI 2011, Revised Selected Papers," .
  151. J. Peyre, J. Smith, J. Jomier, F. Castellano, S. Aylward, and M. Castill, "Systemic Lupus Erythematosus CNS Vasculitis: circulatory pathology demonstrated with perfusion MRI," .
  152. P. Reynolds, J. Jomier, and S. Aylward, "Midas Module for Accessing Slicer Tutorial Data," .
  153. D. Testi, G. Clapworthy, S. Aylward, A. Frangi, and R. Christie, "Interactive visualization of multiscale biomedical data: an integrated approach,"pp. 3-4.
  154. T. Yoo et al., "Special Issue on ITK," Medical Image Analysis, vol. 9, no. 6 .