Medical Computing

Our medical computing team develops algorithms and custom software for researchers, product developers, and clinicians. To do so, we partner with universities on grants from the National Institutes of Health and with commercial companies on product development. We have worked with the University of North Carolina at Chapel Hill, for example, to develop a novel ultrasound-based approach to cancer detection and diagnosis; Brigham and Women’s Hospital to create 3D Slicer; and SonoVol to build an imaging system for high-throughput longitudinal animal studies.

We also have a long history leading and contributing to open source platforms that serve as the foundation of many medical visualization and data processing tools. We were one of the original creators of the Insight Toolkit (ITK), which is the industry standard for medical imaging applications. We also lead the 3D Slicer project.

Customer Highlights

Exonicus and Kitware Collaborate to Develop a Trauma Simulator Using the Pulse Physiology Engine

Introduction The top three causes of preventable death on the battlefield are hemorrhage, tension pneumothorax, and airway trauma. Training to appropriately treat these injuries is … Read More

Xoran Technologies and Kitware Collaborate on Image-guided Platform for Deep Brain Stimulation Surgery

Introduction Deep brain stimulation (DBS) has become a standard of care for Parkinson’s patients and is a more effective treatment than other nonsurgical ones for … Read More

Kitware customer highlight: Radiopharmaceutical Imaging and Dosimetry, LLC (RAPID)

Introduction Radiopharmaceutical therapy (RPT) is a new and underutilized cancer therapy modality that has shown tremendous potential and is the subject of intense recent interest. … Read More

Kitware customer highlight: MuriPlan from Xstrahl – A 3D Slicer based radiotherapy treatment planning system

Introduction Kitware provides collaborative research, development, and technology-integration services for companies that work in the medical and biomedical business sectors. As part of a series … Read More

Kitware customer highlight: Optics in Medicine Laboratory

Introduction Kitware provides collaborative research, development, and custom development and technology-integration services for universities and research centers that work in the medical and biomedical business … Read More

Kitware customer highlight: Phoenix Research Labs

Phoenix Research Labs: The Company Phoenix Research Labs develops technologies to support eye and eye-brain research using mice and rats, with products which are designed … Read More

Areas of Focus

Example of surgical planning, guidance, and/or simulation software

Surgical Planning, Guidance, and Simulation

The applications we develop fuse multiple imaging modalities and robust algorithms to assist physicians before and during surgery. Our physiology simulation software, for example, can be used in virtual environments, training with manikins, and clinical research. Other applications include a technique for performing liver lesion biopsies and a system for analyzing craniosynostosis.

Example of medical image analysis software

Medical Image Analysis

We have open source algorithms for vessel modeling, a computer-aided diagnosis system for research in acute stroke patients, and an approach that uses acoustic angiography to measure small changes in microvessels. We can suit these to other pre-clinical and clinical investigations, as well as to additional neurovascular conditions such as sickle cell disease, Moyamoya disease, aneurysms, post-traumatic stress disorder, and traumatic brain injuries.

Ultrasound Image Systems

We drive pre-clinical research, pre-hospital patient triage, and post-hospital patient monitoring by developing systems for ultrasound image analysis. These systems integrate software applications with medical devices and other hardware. Our approaches enable the use of low-cost ultrasound equipment in a broad range of clinical contexts by relatively less-experienced medical personnel.

Example of cross-platform Interactive Application

Cross-platform Interactive Applications

We work on a variety of interactive web and mobile applications, which span from platforms that run semi-automated image analysis tasks to software that supports Q-Review of segmentation and registration results. These applications work on iOS and Android platforms. They not only leverage our expertise in medical image visualization, but they implement our high-quality software process and data management technology.

Example of digital pathology

Digital Pathology and Medical Visualization

The open source digital pathology software we support offers remote collaboration on a variety of devices over standard networks. While initially targeted to pathology applications, we can readily adapt this infrastructure to other uses in medical visualization.

Example of craniofacial image

Dental and Craniofacial Image Exploration

Our methods to quantitatively explore diseases and the conditions of the craniomaxillofacial (CMF) complex aim to improve early diagnosis, treatment planning, and outcome monitoring. Additional methods analyze bony structures in the skull from computed tomography images. We also design quantitative protocols to improve cranial reconstruction and orthognathic surgery.

What We Offer for Your Project

We provide custom research and software development, collaboration, support, training, and books to help in the above areas of focus.

Medical Computing Platforms

The Insight Toolkit (ITK) is a software development solution for medical image processing, segmentation, and registration. ITK is a library of segmentation and registration imaging algorithms tailored for medical investigations. The toolkit supports a variety of imaging data formats.

3D Slicer

3D Slicer is a medical image computing and visualization application. 3D Slicer works with optical imaging, MRI, CT, and ultrasound data. We have applied 3D Slicer to a range of research and commercial applications.

Logo for Pulse Physiology Engine

The Pulse Physiology Engine has an explorer with models for anaphylaxis and multi-trauma. The engine also contains physiological systems and a common data model.

Logo for the interactive Medical Simulation Toolkit

The interactive Medical Simulation Toolkit (iMSTK) provides developers with software for making virtual simulators for medical procedures, including biopsies, resectioning, radiosurgery, and laparoscopy.


We have over 350 publications on topics such as surgical simulation, medical image analysis, structural shape analysis, and ultrasound image systems. These publications show up in leading conferences and journals.